Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature
Identifieur interne : 000644 ( Main/Exploration ); précédent : 000643; suivant : 000645Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature
Auteurs : Keisuke Matsuo [Japon] ; Takashi Ishiguro [Japon] ; Takatomo Najama [Japon] ; Yoshihiko Shimizu [Japon] ; Yasuhito Kobayashi [Japon] ; Makoto Mutou [Japon]Source :
- Internal Medicine [ 0918-2918 ] ; 2019.
Abstract
A 62-year-old man presented to our hospital for the further evaluation and treatment of his back pain, general fatigue, and dyspnea, which had developed 4 days after the 29th administration of nivolumab to treat his lung cancer. Based on his clinical history, elevated serum cardiac enzyme values, and cardiac magnetic resonance (CMR) imaging and myocardial biopsy findings, he was diagnosed with myocarditis induced by nivolumab. Corticosteroid therapy improved his condition, and CMR performed on hospital day 11 also showed remarkable improvement. Although nivolumab-induced myocarditis is rare, cardiologists should consider it when encountering patients treated with such a drug for malignant disease.
Url:
DOI: 10.2169/internalmedicine.2596-18
PubMed: 31118387
PubMed Central: 6746646
Affiliations:
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type="wicri:Area/Main/Exploration">000644</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Nivolumab-induced Myocarditis Successfully Treated with Corticosteroid Therapy: A Case Report and Review of the Literature</title><author><name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea><wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Cardiology, Saitama Medical University International Medical Center, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Cardiology, Saitama Medical University International Medical Center</wicri:regionArea><wicri:noRegion>Saitama Medical University International Medical Center</wicri:noRegion></affiliation></author><author><name sortKey="Ishiguro, Takashi" sort="Ishiguro, Takashi" uniqKey="Ishiguro T" first="Takashi" last="Ishiguro">Takashi Ishiguro</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center</wicri:regionArea><wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion></affiliation></author><author><name sortKey="Najama, Takatomo" sort="Najama, Takatomo" uniqKey="Najama T" first="Takatomo" last="Najama">Takatomo Najama</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, 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of Pathology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pathology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea><wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion></affiliation></author><author><name sortKey="Mutou, Makoto" sort="Mutou, Makoto" uniqKey="Mutou M" first="Makoto" last="Mutou">Makoto Mutou</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Cardiology, Saitama Cardiovascular and Respiratory Center, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Cardiology, Saitama Cardiovascular and Respiratory Center</wicri:regionArea><wicri:noRegion>Saitama Cardiovascular and Respiratory Center</wicri:noRegion></affiliation></author></analytic><series><title level="j">Internal Medicine</title><idno type="ISSN">0918-2918</idno><idno type="eISSN">1349-7235</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>A 62-year-old man presented to our hospital for the further evaluation and treatment of his back pain, general fatigue, and dyspnea, which had developed 4 days after the 29th administration of nivolumab to treat his lung cancer. Based on his clinical history, elevated serum cardiac enzyme values, and cardiac magnetic resonance (CMR) imaging and myocardial biopsy findings, he was diagnosed with myocarditis induced by nivolumab. Corticosteroid therapy improved his condition, and CMR performed on hospital day 11 also showed remarkable improvement. Although nivolumab-induced myocarditis is rare, cardiologists should consider it when encountering patients treated with such a drug for malignant disease. </p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Semper, H" uniqKey="Semper H">H Semper</name></author><author><name sortKey="Muehlberg, F" uniqKey="Muehlberg F">F Muehlberg</name></author><author><name sortKey="Schulz Menger, J" uniqKey="Schulz Menger J">J Schulz-Menger</name></author><author><name sortKey="Allewelt, M" uniqKey="Allewelt M">M Allewelt</name></author><author><name sortKey="Grohe, C" uniqKey="Grohe C">C Grohe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tay, Ry" uniqKey="Tay R">RY Tay</name></author><author><name sortKey="Blackley, E" uniqKey="Blackley E">E Blackley</name></author><author><name sortKey="Mclean, C" uniqKey="Mclean C">C McLean</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gibson, R" uniqKey="Gibson R">R Gibson</name></author><author><name sortKey="Delaune, J" uniqKey="Delaune J">J Delaune</name></author><author><name sortKey="Szady, A" uniqKey="Szady A">A Szady</name></author><author><name sortKey="Markham, M" uniqKey="Markham M">M Markham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tadokoro, T" uniqKey="Tadokoro T">T Tadokoro</name></author><author><name sortKey="Keshino, E" uniqKey="Keshino E">E Keshino</name></author><author><name sortKey="Makiyama, A" uniqKey="Makiyama A">A Makiyama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tajmir Riahi, A" uniqKey="Tajmir Riahi A">A Tajmir-Riahi</name></author><author><name sortKey="Bergmann, T" uniqKey="Bergmann T">T Bergmann</name></author><author><name sortKey="Schmid, M" uniqKey="Schmid M">M Schmid</name></author><author><name sortKey="Agaimy, A" uniqKey="Agaimy A">A Agaimy</name></author><author><name sortKey="Schuler, G" uniqKey="Schuler G">G Schuler</name></author><author><name sortKey="Heinzerling, L" uniqKey="Heinzerling L">L Heinzerling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Norwood, Tg" uniqKey="Norwood T">TG Norwood</name></author><author><name sortKey="Westbrook, Bc" uniqKey="Westbrook B">BC Westbrook</name></author><author><name sortKey="Johnson, Db" uniqKey="Johnson D">DB Johnson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tawbi, Ha" uniqKey="Tawbi H">HA Tawbi</name></author><author><name sortKey="Forsyth, Pa" uniqKey="Forsyth P">PA Forsyth</name></author><author><name sortKey="Algazi, A" uniqKey="Algazi A">A Algazi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Db" uniqKey="Johnson D">DB Johnson</name></author><author><name sortKey="Balko, Jm" uniqKey="Balko J">JM Balko</name></author><author><name sortKey="Compton, Ml" uniqKey="Compton M">ML Compton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kimura, T" uniqKey="Kimura T">T Kimura</name></author><author><name sortKey="Fukushima, S" uniqKey="Fukushima S">S Fukushima</name></author><author><name sortKey="Miyashita, A" uniqKey="Miyashita A">A Miyashita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heinzerling, L" uniqKey="Heinzerling L">L Heinzerling</name></author><author><name sortKey="Ott, Pa" uniqKey="Ott P">PA Ott</name></author><author><name sortKey="Hodi, Fs" uniqKey="Hodi F">FS Hodi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matson, Dr" uniqKey="Matson D">DR Matson</name></author><author><name sortKey="Accola, Ma" uniqKey="Accola M">MA Accola</name></author><author><name sortKey="Rehrauer, Wm" uniqKey="Rehrauer W">WM Rehrauer</name></author><author><name sortKey="Corliss, Rf" uniqKey="Corliss R">RF Corliss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fukasawa, Y" uniqKey="Fukasawa Y">Y Fukasawa</name></author><author><name sortKey="Sasaki, K" uniqKey="Sasaki K">K Sasaki</name></author><author><name sortKey="Natsume, M" uniqKey="Natsume M">M Natsume</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Detterbeck, Fc" uniqKey="Detterbeck F">FC Detterbeck</name></author><author><name sortKey="Boffa, Dj" uniqKey="Boffa D">DJ Boffa</name></author><author><name sortKey="Kim, Aw" uniqKey="Kim A">AW Kim</name></author><author><name sortKey="Tanoue, Lt" uniqKey="Tanoue L">LT Tanoue</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolchok, Jd" uniqKey="Wolchok J">JD Wolchok</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Varricchi, G" uniqKey="Varricchi G">G Varricchi</name></author><author><name sortKey="Galdiero, Mr" uniqKey="Galdiero M">MR Galdiero</name></author><author><name sortKey="Marone, G" uniqKey="Marone G">G Marone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mahrholdt, H" uniqKey="Mahrholdt H">H Mahrholdt</name></author><author><name sortKey="Goedecke, C" uniqKey="Goedecke C">C Goedecke</name></author><author><name sortKey="Wagner, A" uniqKey="Wagner A">A Wagner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brahmer, Jr" uniqKey="Brahmer J">JR Brahmer</name></author><author><name sortKey="Lacchetti, C" uniqKey="Lacchetti C">C Lacchetti</name></author><author><name sortKey="Schneider, Bj" uniqKey="Schneider B">BJ Schneider</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name></noRegion><name sortKey="Ishiguro, Takashi" sort="Ishiguro, Takashi" uniqKey="Ishiguro T" first="Takashi" last="Ishiguro">Takashi Ishiguro</name><name sortKey="Kobayashi, Yasuhito" sort="Kobayashi, Yasuhito" uniqKey="Kobayashi Y" first="Yasuhito" last="Kobayashi">Yasuhito Kobayashi</name><name sortKey="Matsuo, Keisuke" sort="Matsuo, Keisuke" uniqKey="Matsuo K" first="Keisuke" last="Matsuo">Keisuke Matsuo</name><name sortKey="Mutou, Makoto" sort="Mutou, Makoto" uniqKey="Mutou M" first="Makoto" last="Mutou">Makoto Mutou</name><name sortKey="Najama, Takatomo" sort="Najama, Takatomo" uniqKey="Najama T" first="Takatomo" last="Najama">Takatomo Najama</name><name sortKey="Shimizu, Yoshihiko" sort="Shimizu, Yoshihiko" uniqKey="Shimizu Y" first="Yoshihiko" last="Shimizu">Yoshihiko Shimizu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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